Hyperpigmentation has a number of different causes, it is triggered deeper in the Dermis and can be difficult and require a long-term approach to treatment to treat.
While best results are available by targeting multiple pathways at the same time, Tyrosinase inhibition is the most effective pathway to tackle pigmentation. But it is also the slowest, with treatments often only starting to show results after 1½ to 2 months. Of the Tyrosinase inhibition group, Hydroquinone is the “Gold standard” ingredient, but it has for some time had a cloud over its safety profile and potential to irritate. The evidence for other ingredients in this group which includes Arbutin, Azelaic Acid, and Kojic Acid is not as strong as Hydroquinone, and these ingredients can be irritating and in the case of the Kojic Acid, also have some concerns around their safety. As a result, there has been a significant amount of work done on alternate Tyrosinase inhibition ingredients in the search for one that is safe, well-tolerated, and effective.
A relative newcomer to this group is 4-n-Butylresorcinol – pronounced “4 N beauty resorcinol” – (a.k.a 4nB, 4 Butylresorcinol or Rucinol). The first study on 4nB was published in 1995, but it wasn’t until 2005 that another study was published, with the first trials on humans being published in 2007. Since then, repeated human clinical trials have shown good results, low irritation, high tolerance, and good safety results.
While there have been no head-to-head trials of 4nB and Hydroquinone the relative ability of common Tyrosinase inhibition ingredients to perform their core task has been studied. And when 4nB was compared to Hydroquinone, Arbutin, and Kojic acid, it demonstrated superior tyrosinase inhibition ability.
Another approach for the Reduction of Melanin is: For Eg., Niacinamide reduces the transfer of melanin (carried in melanosomes) to keratinocytes where it is deposited (as pigment) and is an anti-inflammatory that works to regulate the amount of acne-causing oil being produced by the glands in your skin. it regulates skin tone and helps fade the red, purple, and brown marks that acne can leave on the skin. In addition, it reduces the look of stretched pores, Helps reduce hard, clogged bumps & orange-peel texture and visibly improves blotchy tone, and fades post-blemish marks
Having found this, We at REEHDUS BIOTECH created a Unique combination of Highly concentrated Niacinamide 15% + Butylresorcinol to specifically target open pores, hyperpigmentation and age spots using 4-n-Butylresorcinol.
Nithigna –
This has honestly changed my skincare game! I have oily and acne prone skin It done wonders to control the oil production on my face. When ever I use new product my skin get irritated and get pimples but I have been using this product for two weeks
I able to see difference in my face
It reduced my 35% of scars This combined with their anti acne serum and 2% Hyaluronic acid serum are my favourite for the winter months.
Priya –
I finished three bottles of it already. Given my order for the fourth. Been using it from three months now. Quick and satisfying result. My pigmentation gone and skin also looks glowy…
Amrutha –
I have been using this product since last year and it’s an amazing product it reduced my hyperpigmentation and gave me even skin tone. Thank you Reehdus for the amazing product
Sindhu –
Saviour of oily skin
Just go for it… Wonderful for acne-oily &pigmented skin. Helped me a lot with my oily & uneven skin.
Krishna –
I started seeing the difference within 10days itself. Why didn’t I find this product a year back🙄😁
Vivek –
I am using this serum from November 2021. I just loved the product. It was perfect for my skin, it reduced my pimple marks and dark spots on my skin. Thanks for this amazing product
Gunjal –
Niacinamide 15% +butylresorcinol serum
This serum really did wonders for my skin. I have melasma from more than a year. I tried using hydroquinone based cream which is prescribed by a dermatologist, when I stopped using that cream my melasma was increased. This year in January I seen their add in Instagram and purchased this product back to today now my melasma was faded and I’m really happy with the results. Thank you sooo much for this amazing product
Vicky –
I’m using this serum from last 10 days it reduced pimples and spots helped me a lot thank you Reehdus Biotech very very much.
Rutuja –
I started using this serum for my spots and pigmentation. I should really thank this product for helping me out
Keerthi –
When I started using this serum I felt a little bit irritation because I have sensitive skin and this serum is highly concentrated. I contacted their customer service and they really helped me a lot and suggested me a good skincare routine. Now I’m really happy with my skin.. all thanks to REEHDUS BIOTECH for such an amazing products